Cytidine | 65-46-3

ʻO Cytidine kahi mole nucleoside i haku ʻia me ka cytosine nucleobase i hoʻopili ʻia me ka ribosa kō. ʻO ia kekahi o nā poloka kūkulu o RNA (ribonucleic acid) a ke pāʻani nei i nā kuleana koʻikoʻi i ka metabolism cellular a me ka synthesis acid nucleic.

Ke Kinohi Kinohi: Aia ka cytidine i ka pyrimidine nucleobase cytosine i hoʻopili ʻia i ka ribose kōpaʻa ʻelima-carbon ma o kahi paʻa β-N1-glycosidic.

ʻO ka hana olaola: ʻO Cytidine kahi mea koʻikoʻi o RNA, kahi e lawelawe ai ʻo ia kekahi o nā nucleosides ʻehā i hoʻohana ʻia i ke kūkulu ʻana i nā kaula RNA i ka wā transcription. Ma kahi o kāna kuleana i ka RNA synthesis, komo pū ka cytidine i nā ala metabolic like ʻole, me ka biosynthesis o phospholipids a me ka hoʻoponopono ʻana i ka hōʻike ʻana.

Metabolism: I loko o nā pūnaewele, hiki ke phosphorylated ka cytidine e hana i ka cytidine monophosphate (CMP), cytidine diphosphate (CDP), a me ka cytidine triphosphate (CTP), he mau mea koʻikoʻi i ka biosynthesis nucleic acid a me nā kaʻina biochemical ʻē aʻe.

Nā Puna Meaʻai: Loaʻa maoli ka Cytidine i nā meaʻai he nui, e like me ka ʻiʻo, ka iʻa, nā huahana waiū, a me kekahi mau mea kanu. Hiki ke loaʻa iā ia ma o ka ʻai ʻana ma ke ʻano o nā nucleotides me ka nucleic acid.

Hiki i ka Therapeutic Potential: Ua noiʻi ʻia ʻo Cytidine a me kāna mau derivatives no kā lākou hiki ke hoʻohana i ka lāʻau lapaʻau i nā ʻano olakino like ʻole, me nā maʻi neurological, cancer, a me nā maʻi viral. No ka laʻana, hoʻohana ʻia nā analogs cytidine e like me cytarabine i ka chemotherapy e mālama i kekahi mau ʻano leukemia a me lymphoma.