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ʻO Magnolia officinalis extract (inoa Pelekane: Magnolia officinalis PE ), nā mea hana ikaika: a me ka magnolol, magnolol, magnolol total phenol. Puna lāʻau: He mea hoʻoikaika i ka hana antibacterial i ka ʻili o Magnolia officinalis Rehder et Wilson, kahi lāʻau lapaʻau kuʻuna Kina.

He keʻokeʻo keʻokeʻo kēia huahana. Hiki ke hoʻoheheʻe ʻia i loko o ka benzene, ether, chloroform, acetone, hiki ʻole ke hoʻoheheʻe ʻia i ka wai, hiki ke hoʻoheheʻe ʻia i ka hopena alkali dilute e loaʻa ai ka paʻakai sodium. He mea maʻalahi ka hui phenolic hydroxyl, aʻo ka hui allyl e maʻalahi ke hana i ka hopena hoʻohui.

Loaʻa iā ia kahi hopena hoʻomaha kūikawā lōʻihi a me ka hopena antibacterial ikaika, hiki ke kāohi i ka platelet aggregation.

Ma ke kino, hoʻohana nui ʻia ia e like me ka lāʻau antibacterial a me antifungal. Pono e hoʻopaʻa ʻia kēia huahana mai ka mālamalama a mālama ʻia i loko o kahi wahi maloʻo, ʻoluʻolu a maikaʻi.

ʻO ka pono a me ke kuleana o Magnolia Cortex Extract 2% Honokiol： 

Anti-inflammatory

I ka hopena inflammatory, hoʻokuʻu ka phospholipids membrane cell i ka waikawa arachidonic (AA) ma lalo o ka hana a phospholipase A2.

ʻElua ala metabolic no AA, ʻo ia ka hana ʻana i nā prostaglandins a me nā thromboxanes ma ka hana o cyclooxygenase (COX), a ʻo kekahi e hana i nā prostaglandins a me nā thromboxanes ma o ka hana a cyclooxygenase (COX). ʻO ka hana a lipoxygenase (LO) e hana i nā leukotrienes (LT).

ʻO ka Honokiol ma nā kiʻekiʻe kiʻekiʻe i kāohi i ka hana o COX i nā pūnaewele i hoʻopilikia ʻia, ʻoiai ke kāohi nei i ke ala metabolic LO. No laila, ʻo ka honokiol ka mea hoʻopaneʻe ʻelua o COX a me LO.

Hiki ke pili ka hopena anti-inflammatory o ka honokiol i kona pale ʻana i ʻelua ala metabolic o AA. Eia kekahi, hiki i ka honokiol ke pale i ka hoʻokuʻu ʻana o nā enzyme lysosomal, e hoʻemi i ka permeability o nā paia capillary a puni ka wahi o ka mumū, a ke kāohi i ka neʻe ʻana o ka leukocyte a me ka hoʻonui ʻana o ka ʻiʻo fibrous.

Antioxidant

Loaʻa i ka Magnolol a me Honokiol nā hopena scavenging radical manuahi, hiki ke hoʻopaʻa i nā radical parahydroxyl a me ka hydrogen peroxide.

I ka manawa like, hiki iā ia ke pale i ka hana o nā enzymes respiratory chain mitochondrial e kū'ē i ka NADPH-induced peroxidative stress, antagonize i ka hemolysis oxidative o nā ʻulaʻula ʻulaʻula, a ke kāohi i ka lipid peroxidation.

Ua nānā kekahi mau haʻawina in vitro a in vivo i ka hana antioxidant o Magnolia officinalis extract, ʻo ia ka 1000 mau manawa ikaika ma mua o ka alpha-tocopherol.