Adenosine 5′-monophosphate | 61-19-8

ʻO Adenosine 5'-monophosphate (AMP) he nucleotide i haku ʻia me ka adenine, ribose, a me kahi hui phosphate.

Hoʻokumu Kemika: Loaʻa ʻia ka AMP mai ka nucleoside adenosine, kahi i hoʻopili ʻia ai ka adenine me ka ribose, a ua hoʻopili ʻia kahi hui phosphate hou i ka 5' kalapona o ka ribosa ma o kahi paʻa phosphoester.

Koiola: He mea nui ka AMP o nā ʻakika nucleic, e lawelawe ana ma ke ʻano he monomer i ke kūkulu ʻana i nā molekole RNA. I ka RNA, ua hoʻokomo ʻia ka AMP i loko o ke kaulahao polymer ma o nā kaula phosphodiester, e hana ana i ka iwi kuamoʻo o ke kaula RNA.

Energy Metabolism: Hoʻokomo pū ʻia ka AMP i ka metabolism ikehu cellular. He mea mua ia i ka adenosine diphosphate (ADP) a me ka adenosine triphosphate (ATP) ma o ka phosphorylation reactions catalyzed e nā enzymes e like me adenylate kinase. ʻO ATP, ʻo ia hoʻi, kahi mea lawe ikehu mua i nā cell, e hāʻawi ana i ka ikehu no nā kaʻina hana kelepona.

Hoʻoponopono Metabolic: He kuleana ko AMP i ka hoʻoponopono ʻana i ke koena o ka ikehu cellular. Hiki i nā pae AMP kelepona ke loli i ka pane ʻana i nā loli metabolic a me nā koi ikaika. Hiki i nā kiʻekiʻe kiʻekiʻe o AMP pili i ka ATP ke hoʻāla i nā ala ʻike ikehu kelepona, e like me ka AMP-activated protein kinase (AMPK), ka mea e hoʻoponopono i ka metabolism e mālama i ka homeostasis ikehu.

Puna Meaʻai: Hiki ke loaʻa ka AMP mai nā kumu meaʻai, ʻoi aku ka nui o nā meaʻai nui i nā waikawa nucleic, e like me ka ʻiʻo, ka iʻa, a me nā legumes.

Nā noi lāʻau lapaʻau: Ua noiʻi ʻia ʻo AMP a me kāna mau derivatives no nā noi therapeutic kūpono. No ka laʻana, cAMP (cyclic AMP), he derivative o AMP, lawelawe ma ke ʻano he ʻelele ʻelua i nā ala transduction hōʻailona a ua manaʻo ʻia e nā lāʻau lapaʻau like ʻole no ka mālama ʻana i nā maʻi e like me ka hānō, nā maʻi maʻi cardiovascular, a me nā ʻāpana hormonal.