Uridine |58-96-8

ʻO ka Uridine kahi nucleoside pyrimidine e lawelawe ana ma ke ʻano he kahua kūkulu kumu no ka RNA (ribonucleic acid), kekahi o nā ʻano nui ʻelua o nā ʻakika nucleic pono no ka mālama ʻana a me ka lawe ʻana i ka ʻike genetic i loko o nā cell.

Ke Kinohi Kemika: Aia ka uridine i ka uracil kumu pyrimidine i hoʻopili ʻia i ka ribose kōpaʻa ʻelima-carbon ma o ka paʻa β-N1-glycosidic.

Ke kuleana olaola:

RNA Building Block: ʻO Uridine kahi mea koʻikoʻi o ka RNA, kahi e hana ai i ka iwi kuamoʻo o nā molekala RNA me nā nucleosides e like me adenosine, guanosine, a me cytidine.

Messenger RNA (mRNA): I loko o ka mRNA, hoʻopili nā koena uridine i ka ʻike genetic i ka wā o ka unuhi ʻana, e lawe ana i nā ʻōlelo aʻoaʻo mai DNA i ka mīkini synthesis protein i loko o ke kelepona.

Hoʻololi i ka RNA (tRNA): Aia nō ʻo Uridine i nā molekole intRNA, kahi e komo ai i ke kaʻina unuhi ma ka ʻike ʻana i nā codon kikoʻī a me ka hāʻawi ʻana i nā waikawa amino pili i ka ribosome.

Metabolism: Hiki ke hoʻopili ʻia ka uridine de novo i loko o nā cell a i loaʻa mai nā kumu meaʻai.Hana ʻia ia ma o ka hoʻololi enzymatic o orotidine monophosphate (OMP) a i ʻole uridine monophosphate (UMP) i ke ala pyrimidine biosynthesis.

ʻO ke koʻikoʻi o ke kino:

Neurotransmitter Precursor: He kuleana ko Uridine i ka hana o ka lolo a me ka ulu ʻana.He precursor ia no ka synthesis o ka lolo phospholipids, me ka phosphatidylcholine, he mea nui ia no ka pono o ka membrane neuronal a me ka hōʻailona neurotransmitter.

Nā hopena neuroprotective: Ua aʻo ʻia ʻo Uridine no kāna mau waiwai neuroprotective a me kona hiki ke hoʻonui i ka hana synaptic a me ka plasticity neuronal.

Hiki i ka lāʻau lapaʻau:

Ua noiʻi ʻia ʻo Uridine a me kāna mau derivatives no ka hoʻohana ʻana i ka lāʻau lapaʻau i nā maʻi neurological, me ka maʻi o Alzheimer a me nā maʻi ʻeha.

Ua ʻimi ʻia ʻo Uridine supplementation ma ke ʻano he hoʻolālā e kākoʻo i ka hana cognitive a hoʻēmi i nā hōʻailona pili i nā maʻi neurodegenerative.

Nā Puna Meaʻai: Loaʻa maoli ka uridine i nā meaʻai like ʻole, e like me ka ʻiʻo, ka iʻa, nā mea kanu, a me nā huahana waiū.